Ginsenoside Rh2 sensitizes the anti-cancer effects of sunitinib by inducing cell cycle arrest in renal cell carcinoma
Abstract Sunitinib, a VEGF blockade, is used to treat clear cell renal cell carcinoma (ccRCC).However, the anti-cancer treatment effects of sunitinib do not last long in ccRCC patients.Ginsenoside, a natural medicine extracted from ginseng, has been studied in cancer treatment and shown to have anti-tumor effects and low toxicity.We assessed cell v